Please scroll down to see the latest Presentations & Publications
PGS Technology Now Available at Conceptions
Advanced Embryo Genetic Screening
is Available at Conceptions
Click here to view a presentation on
Preimplantation Genetic Screening Care
For more information contact:
Dana Ackerman, Marketing
Conceptions Reproductive Associates of Colorado
271 W. County Line Road, Littleton, CO 80129, 303-738-5330
For Immediate Release:
May 1st, 2008
CONCEPTIONS REPRODUCTIVE ASSOCIATES IS THE FIRST IN COLORADO TO TEST ALL 24 CHROMOSOMES WITH HIGH RELIABILITY
Littleton, Co. — Assisted Reproductive Technologies (ART) includes a variety of treatment options such as in vitro fertilization (IVF) which have helped thousands of previously infertile couples to conceive. Screening embryos for chromosome errors has been shown to improve a couple’s chances of conceiving and delivering a health baby through in-vitro fertilization (IVF). This may be particularly important for women above the age of 35, women with a prior history of miscarriage, and women that have had an unsuccessful IVF cycle. Of late, many news stories have focused on several strategies to achieve this goal that have fallen short and have proven to be unreliable. The first technique used, called FISH (fluorescent in situ hybridization), involves analysis of only 9 chromosomes – but this leaves 15 of 24 human chromosomes unchecked. A newer technique is comparative genomic hybridization or CGH. While this is able to check all 24 chromosomes, it takes up to five days to perform so that a couple must freeze their embryos and transfer them at a later date.
Conceptions is partnering with Gene Security Network to bring patients a new and advanced technology: single nucleotide polymorphism microarray analysis with the critical addition of Parental SupportTM bioinformatics technology. Parental SupportTM achieves a high degree of accuracy(1) by incorporating genetic data from the parents derived from DNA collected through a simple cheek swab.
The test has rapid turnaround allowing a woman to have an embryo transfer in the same cycle that she undergoes IVF. Conceptions is pleased to be the only group in Colorado, and one of five leading IVF centers in the country, to first offer this cutting edge technology later this year.
About Gene Security Network:
Gene Security Network (GSN) specializes in combining bioinformatic analysis with leading laboratory techniques to deliver highly accurate full-genome testing on small quantities of biological material. GSN’s proprietary testing technology, called Parental SupportTM, will be used for preimplantation genetic diagnosis to guide doctors in screening embryos for disease susceptibility during in-vitro fertilization. The company and their testing laboratory are based out of Redwood City, California. For more information please visit www.genesecurity.net.
(1)Johnson D.S., et al, Fertility & Sterility,
Volume 89, Issue 4, Suppl, April 2008, p S5.
For more information or to schedule an
interview, call 303-738-5330.
Recent Presentations & Publications
Recent Presentations/Publications
The Midwest Reproductive Symposium, Chicago, IL, June 2010
IVF Protocols: Hyper & Hypo-Responders, Implantation
Mark R. Bush, MD, Oral Presentation
Optimizing IVF Protocols
Mark R. Bush, MD, Postgraduate Workshop
Comprehensive Mechanistic Analysis of Aneuploidy in Cleavage Stage IVF Embryos
Johnson DS1,10, Ross R2, Thormahlen S3, Khoury C4, Barritt J5, Behr B6, Blauer K7, Boostanfar R8, Bush M3, Lathi
R6, Le A8, Potter D1,4, Smotrich D2, Wilson M9, Cinnioglu C1, Gemelos G1, Hill M1, Pettersen B1, Ryan A1,
Rabinowitz M1
Human Reproduction, submitted
The Pacific Coast Reproductive Society
has received the abstract "MENOPUR® VERSUS RFSH IN GNRH ANTAGONIST CYCLES" for consideration as an
oral or poster presentation at the 2010 PCRS Annual Meeting in April, 2010. M.R. Bush, co-author.
Impact of IVF Protocol Selection
Invited lectures given in 2009 in Las Vegas, NV, Birmingham, AL, Ft. Lauderdale, FL, Boston, MA, La Jolla, CA,
Honolulu, HI, and Los Angeles, CA.
Menopur® versus rFSH in GnRH antagonist cycles
C.E. Miller, E. Zbella, B.W. Webster, K.J. Doody, M.R. Bush, S.F. Dorfman
Fertility and Sterility
September 2009 (Vol. 92, Issue 3, Page S150)
33rd National Primary Care Practitioner Symposium, Keystone, CO, July 2008
Fertility Care Update for Nurse Practitioners
Mark R. Bush, MD, FACOG, FACS, Oral Presentation
The American Society for Reproductive Medicine Annual Meeting, Washington, DC, October 2007
Selective cut-back protocol for in-vitro fertilization (IVF) ovarian stimulation in patients with polycystic ovary syndrome (PCOS)
M.R. Bush, Poster Presentation
Selective cut-back protocol for in-vitro fertilization (IVF) ovarian stimulation in patients with polycystic ovary syndrome (PCOS)
M.R. Bush, M.S. Swanson, S. Stephan, B.H. Albrecht
Fertility and Sterility
September 2007 (Vol. 88, Page S293)
Pacific Coast Reproductive Society 2006 Annual Meeting Program and Postgraduate Courses Page
LH Activity: When and How Much?
Mark Bush, MD, Oral Presentation
Fertility and Sterility
April 2006 (Vol. 85, Page S3)
Treatment with gonadotropin-releasing hormone (GnRH) antagonists in women suppressed with GnRH agonist may avoid cycle cancellation in patients at risk for ovarian hyperstimulation syndrome
Robert L. Gustofson, Frederick W. Larsen, Mark R.Bush, James H. Segars
Fertility and Sterility
January 2006 (Vol. 85, Issue 1, Pages 251-254)
The novel use of ganirelix to rescue hyperresponding stimulation cycles from cancellation in patients treated with microdose lupron
R.L. Gustofson, M.R. Bush, J.H. Segars, F.W. Larsen
Fertility and Sterility
September 2004 (Vol. 82, Pages S32-S33)