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Conceptions Reproductive Associates of Colorado
Littleton, CO Phone:303-794-0045    Denver, CO Phone:303-720-7887    Lafayette, CO Phone:303-449-1084 
Fertility Clinic & IVF Doctors near Denver, CO - Conceptions Reproductive Associates of Colorado
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In vitro fertilization (IVF) Program
Chromosome Assessment & Preimplantation Genetic Diagnosis (PGD) or Preimplantatiion Genetic Screening (PGS)

> IVF Program
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- Chromosome Assessment, PGD-PGS
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 Natera, Inc. (formerly Gene Security Network)

We collaborate with Natera, Inc. to offer preimplantation genetic diagnosis (PGD) for full chromosome screening of embryos and/or single gene testing.  Natera utilizes a SNP Microarray testing platform plus their proprietary Parental Support TM technology which is the most accurate and comprehensive PGD testing available.   Conceptions,  a leader in IVF and ART technologies, is proud to be one of the first 5 centers to begin utilizing this advanced technology since its launch in early 2009.  

All technologies for PGD chromosome screening are designed to test embryos for chromosome problems and aid physicians in identifying those embryos that are most likely to implant and lead to healthy babies.  Parental Support technology goes a step further than other technologies by utilizing DNA from both parents along with carefully designed bioinformatic algorithms to accurately and reliably test cells from each embryo.  Testing analyzes all 22 numbered chromosomes plus the sex chromosomes X and Y.  Only Parental Support can detect other abnormalities such as haploidy and all types of triploidy (when there are missing or extra whole sets of chromosomes), chromosomal deletions and duplications, UPD (Uniparental Disomy), cell contamination, and also determine if abnormalities detected are maternal or paternal in origin.  

Recent data suggests that utilizing a 24 chromosome SNP array for chromosome screening of embryos improves both the implantation rate and pregnancy rate for women of advanced maternal age when a euploid embryo transfer takes place, thus reducing the negative effects of advanced maternal age (Rabinowitz, M. presented at the 2010 meetings of the American Society of Reproductive Medicine). 

Conceptions also offers PGD testing for chromosome translocations and single gene disorders such as cystic fibrosis, spinal muscular atrophy, and fragile X syndrome  with the option for simultaneous chromosome screening through Natera.
 
Please compare our pricing and the unique ability of the Natera test which, in the case of an abnormal embryo, can determine if it was caused by the egg or sperm.
 
For those without insurance, Conceptions cash charges are capped at 19,125 and includes:  Pre-IVF cycle testing, full IVF cycle management including all ultrasounds and bloodwork, egg retrieval, ICSI, day 5 embryo laser placental biopsy, Natera full 23 pair chromosomal assessment, cryopreservation and subsequent frozen embryo transfer cycle.
 
To learn more about genetic screening of embryos view the articles and video below, or visit: www.Natera.com

 Embryo Chromosome Assessment

CONCEPTIONS REPRODUCTIVE ASSOCIATES IS THE FIRST IN COLORADO TO TEST ALL 24 CHROMOSOMES WITH HIGH RELIABILITY

Littleton, Co. — Assisted Reproductive Technologies (ART) includes a variety of treatment options such as in vitro fertilization (IVF) which have helped thousands of previously infertile couples to conceive. Screening embryos for chromosome errors has been shown to improve a couple’s chances of conceiving and delivering a health baby through in-vitro fertilization (IVF). This may be particularly important for women above the age of 35, women with a prior history of miscarriage, and women that have had an unsuccessful IVF cycle. Of late, many news stories have focused on several strategies to achieve this goal that have fallen short and have proven to be unreliable. The first technique used, called FISH (fluorescent in situ hybridization), involves analysis of only 9 chromosomes – but this leaves 15 of 24 human chromosomes unchecked. A newer technique is comparative genomic hybridization or CGH. While this is able to check all 24 chromosomes, it takes up to five days to perform so that a couple must freeze their embryos and transfer them at a later date.

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