What is IVF Embryonic Screening?
PGT-A, or preimplantation genetic testing for aneuploidies is used to determine if the embryo has a balanced set of chromosomes, or euploid. Embryos that have too few or too many chromosomes or aneuploid are highly unlikely to produce a healthy pregnancy. With PGT-A, only chromosomally balanced embryos are chosen for embryo transfer. This increases the chance of pregnancy and reduces the risk of miscarriage.
PGT-M, or preimplantation genetic testing for monogenic/single gene defects, is performed prior to pregnancy reducing the risk of delivering an affected child. Patients who are at high risk for passing on genetic diseases such as Tay-Sachs, BRACA I, or BRCA II, are recommended to use PGT-M. Unlike PGT-A, PGT-M tests for specific genetic defects.
PGT-SR, or preimplantation genetic testing for structural rearrangement, is used to confirm that embryos have the correct amount of genetic material. Embryos with an incorrect amount will lead to a failed pregnancy.